CBD oil can be used to treat a host of illnesses such as seizures, anxiety, nausea, stress, arthritis, back pain, cancer, gastrointestinal issues, and so much more. But now we’re not just talking about humans, we’re talking about treating your beloved dog.
Just like in your own body, cannabinoids in marijuana interact with your dog’s endocannabinoid system. Dogs have a series of receptors that run through their body, and the cannabinoids interact with these receptors, modulating pain, anxiety, and nausea. Unlike other drugs, medical cannabis has no life-threatening side effects when the proper dosage is used. It will not damage your dog’s kidney, liver, or GI tract. Lastly, your dog will never be high or sedated.
We have already learned that there are several applications for CBD, and each of these applications is met with various levels of evidence. There are still ongoing clinical trials that evaluate its ability to help with various human and pet disorders. From these clinical trials we are able to evaluate the potential safety implications and the overall effectiveness of CBD as a treatment. Animal studies have been the predominant means of testing its usefulness.
Let’s discuss even further why CBD oil can have such a remarkable effect on your dog. CBD has a rather “promiscuous pharmacology,” meaning that it acts upon a number of nerve receptors in the brain and body, and this includes cannabinoid receptors. The doggy brain, like your own, has a number of highly specialized cells called neurons. These neurons connect to the other synapses in the brain. At these sites, the neurons communicate to one another and release chemical messages that we call neurotransmitters. The neuron will be sensitive to a neurotransmitter that fits into that transmitter. This is like an electrical outlet with a plug in it.
When the plug fits, as it were, then the neuron can respond directly to that transmitter. Otherwise, it can’t respond at all. Neurons have many neurotransmitter receptors, which means that they can respond to many neurotransmitters, but not to all of them.
Some neurotransmitters are produced within the body, while others are created outside the body, such as from plants. Plant cannabinoids like CBD and THC are a case in point. When your dog consumes edible CBD, compounds enter their body, then their bloodstream, and finally into their brain. Once they’re there, the plant-based compounds can influence neurons. They can’t interact with all neurons, but they do with those that have the right receptors.
CBD is so powerful because it influences many receptors in your dog’s system. CBD is “non-psychoactive” because it influences their receptors indirectly, as opposed to directly. The receptors that it influences are CB1 and CB2. It also can increase your dog’s natural level of endocannabinoids by inhibiting the enzyme that breaks them down.
It’s also worth noting that CBD influences the non-cannabinoid receptors as well. It can interact with a number of receptors sensitive to a variety of drugs and neurotransmitters. The list includes opioid receptors, which help with pain regulation. These are the very receptors that are the target of the drug industry, and can lead to abuse of heroin and morphine in humans. CBD interacts with these receptors and can help regulate cognition and behavior.
It’s where CBD interacts with the serotonin system that so much potential lies. It can target the 1A serotonin receptor, which is associated with countless therapeutic possibilities.
A pharmacologist from the University of Aberdeen named Professor Roger Pertwee has this to say about CBD biology:
“It’s apparent ability to enhance the activation of serotonin 1A receptors supports the possibility that it could be used to ameliorate disorders that include: opioid dependence, neuropathic pain, depression and anxiety disorders, nausea and vomiting (e.g. from chemotherapy), and negative symptoms of schizophrenia,” he said. “One big unanswered question is what the human clinical relevance and importance of each of these potential therapeutic uses of CBD, identified solely by examining data from non-human preclinical research, actually is.”
Understanding the neurological effects of CBD is rather complicated. This is because there are so many receptors that it interacts with. But the complexity itself might be the very reason why it’s so powerful as a therapeutic agent. Anxiety is known as a motivational disorder, and we forget that our dogs can suffer from this just as much as we do! It is terribly complex because it involves multiple receptor systems and neural networks throughout the brain. But, because CBD is complex, and shows multi-target effects, it might therefore be the perfect agent for aiding in the treatment of this disorder. More research is needed to truly mine the potential of CBD.
If you think you’d like to give CBD oil a try for your dog, just be sure to start with a low dose and gradually increase it to see how it affects your dog. And of course always buy a high quality product from a reputable dealer like CBD Pure.
So, as you can see, CBD works biologically with our dogs’ bodies to produce the marvelous effects that it does. This interaction with the compound is safe, effective, and could be life-changing for your pet. The more we learn about CBD, the more that we’re going to discover. And time can only tell just how many receptors, and how much potential, there is with the compound. In the end, CBD oil reminds us of how remarkably similar our systems are to that of our furry friends.